There's an open source application plugin written in .NET I occasionally contribute to. As a regular part of my workflow, I sometimes have to attach the debugger to the application with the plugin loaded to troubleshoot unexpected behavior. When I did that the last time, the breakpoints in Visual Studio for some reason didn't work.
SlowCheetah is a very useful Visual Studio extension which builds upon Visual Studio's built-in support for Web.config transformations. It adds similar XDT transformation file support to non-web projects which can be used even during debugging, while built-in solution for web projects only works for web deployment. There is already a feature request for SlowCheetah for it, but until it's implemented, you'll need to find a different solution.
The 1.3.0.2918 build of CruiseControl.NET has an error in `msbuild.xsl` file which causes an XslLoadException to be thrown when trying to view the MSBuild output in the web dashboard.